Book /Livre

Voilà mon livre « Marc L’invincible » est désormais en ligne et disponible* à l’achat dans la boutique Kindle: ( en français)

« Marc L’invincible: L’histoire vraie d’une récupération remarquable, après arrêt cardiaque et lésions cérébrales anoxiques », est désormais disponible en livre broché dans la boutique Amazon. Les lecteurs peuvent l’acheter:

Here is my book « Marc L’invincible » is now online and available * for purchase in the Kindle store: (in French)

I will do English translation ( just give me some time)

Ici lien vers page de Écrivain-biographe basée à Grenoble -Membre des Compagnons Biographes – Julie Lucquet qui à prêter son plume pour raconter notre histoire :

We are starting soft hbot for Marc:

I honestly believe that soft chamber can also help in many ways but I think it’s not the best for a period of time right after his injury but on the other hand 100% oxygen has more potential right after an injury from my point of view.

I’ll be honest; I do understand that parents can’t always go to clinics every year, or twice a year for 2 months…. ( in order to do 40 dives).

Just to give you an exemple:

We did four months in Israel’s Hbot back in 2016 ( which was the best thing that could happened to Marc) so it was the period when oxygen 100% helped him mostly and it was more potential because more close to injury in time.

we also did one month in 2017 and then two months in 2018

So in total we did 110hours of hard chamber (1,5ata 100% oxygen) in 3 years.

Both of the two last times, we saw progress which was much less obvious than at his first time in 2016 and it’s totally normal.

So now we are sold on soft chamber: it’s obvious it still helps him but I really think that I would do it now at 1,3 ata without oxygen, not because it’s my favorite protocol, but because it’s safe for home use. In those circumstances it would give less results but everyone is able to do it at home which by the way makes it 50% more oxygen in his plasma that will help him.

So it’s just obvious, we can not escape school every year for 2 months. So I believe that a soft chamber can be THE solution for long term treatment (we are talking years after the acute injury).

And by the way we have some good canadien group testimonials from parents (in french only) who mostly used soft chamber treatments only.

Here’s our chamber installation :


Jean-François Tremblay


It was an exeptional experience, very helpful for installation and for all of my questions and just perfectioning training.


Nous commençons souple hbot pour Marc:

Honnêtement, j’ai la conviction que la chambre souple peut aussi aider de nombreuses manières, mais j’estime que ce n’est pas la meilleure solution pour une période qui suit immédiatement sa anoxie cérébrale , mais que 100% d’oxygène a au plus de potentiel après son arrêt cardiaque (c’est que de mon point de vue) …après 110h chambre dure 100% oxygene et 1,5 ata on passe à chambre souple à la maison 1,3 ata et sans oxygène et après 3 ans!

Je serai honnête; Je comprends que les parents ne peuvent pas toujours aller aux cliniques chaque année, une ou deux fois par an pendant 2 mois … (pour faire 40 plongées).

Juste pour vous donner un exemple:

On a fait pendant 3 ans En Israël, nous avons Hbot dure (1,5 ata 100% oxygène) –

pendant quatre mois en 2016 (ce qui a été la meilleure chose qui puisse arriver à Marc). C’est donc la période où l’oxygène à 100% l’a aidé le plus, ce qui lui donnait plus de potentiel, car il était plus proche de son anoxie cérébrale dans le temps.

nous avons également fait un mois en 2017 puis deux mois en 2018

Au total, nous avons donc effectué 110 heures de chambre dure (1,5% à 100% d’oxygène) en 3 ans.

Les deux dernières fois, nous avons constaté des progrès beaucoup moins évidents que lors de sa première fois en 2016 et c’est tout à fait normal.

Nous sommes maintenant commence le chambre souple : c’est évident que peut l’aider toujours, mais je pense vraiment que je le ferais maintenant à 1,3 ata sans oxygène, non pas parce que c’est mon protocole préféré, mais parce que c’est sans danger pour la maison. Dans ces circonstances, cela donnerait moins de résultats, mais tout le monde est capable de le faire à la maison, ce qui lui donne 50% d’oxygène supplémentaire dans son plasma, ce qui l’aidera.

C’est donc évident, nous ne pouvons pas échapper de l’école tous les ans pendant 2 mois. Je pense donc qu’une chambre souple peut être LA solution pour un traitement à long terme (nous parlons des années après anoxie cérébrale).

Et au fait, nous avons de bons témoignages de groupes canadiens de la part de parents qui utilisaient principalement des traitements de chambre souple :

Voici notre installation de chambre:


Jean-François Tremblay

Si vous voulez contact:

Tel france : 0186655685

Ce fut une expérience exceptionnelle, très utile pour l’installation et pour toutes mes questions et pour perfectionner ma formation.

So why Hbot works not always same way in brain injury?

So why Hbot works not always same way in children’s? I am not a doctor I am just a mum like you so please I do analyze my son injury I read a lot but I am not a doctor ( take it just only mum reflection on subject) ok?

It’s very difficult question and I think even best Hbot doctors don’t know exact answer honestly

Let’s say : first of all each brain injury is unique and diferent.

I am trying just analyzing what I can as dates but as I said with anoxic brain injuries we don’t have any studies with spect scans so all this discussion just my personal suppositions ok ?

Ok i post mri of Marc before Hbot and after 80h

We have MRI in January 2016 just some days after anoxic injury

And we have MRI June 2017 after 80h Hbot … but without general anesthesia ( so some artifacts)

Be my guest if any radiology specialist want to make professional hole comparison

1. I think Age of child in the moment of injury play very big role : of child very small ( new born or HIE child for example) smaller is a child at brain injury more fragile his brain ( so same 25 minutes without oxygen will be more devastating on smallest child brain at birth or 1 month age than at 4 years old)

Second why age is important – because if child was already walking / full functioning child before brain injury -so after it will be retraining of his lost functions wile in new born it will be just training ( with less neurons in brain) I think it’s more difficult. But it’s just my opinion.

2. Of cause most important factor : it’s volume of Brain which was damaged!!!!

While there is no way of knowing how much recoverable tissue exists in the days, weeks, and years following brain injury , HBOT can increase cell reproduction and administer oxygen to tissue that was previously cut off from blood flow. The dormant cells surrounding the damaged tissue area, also known as ischemic penumbra, are responsible for much of post-stroke dysfunction. If oxygen therapy can revive these cells, lost functionality may return to the individual.

And this you can say only by MRI and Spect. But again for small children’s I am sorry but MRI don’t give exact informations ( that’s why neurologists don’t like to do MRI for cp children’s too early age …. we can really see at age 4-5 years but before it’s very difficult).

But still : Qualitative assessment of brainstem injury on T1 and T2 images in neonates with HIE may provide information on injury severity and risk of death, but objective quantitative data such as ADC values are lacking. ( if you want to read about read this study:

These infratentorial areas have high concentrations of excitatory neurotransmitters (e.g., glutamate) and are especially vulnerable to the profound hypoxia-ischemia that is typical in HIE. The cerebellum acts as a satellite system of established cortico-basal ganglia networks in neonates.

If we talk about MRI of my child ( he had basal ganglia

and thalamus damages) …

In one large study cohort, 60% to 70% of infants who sustained moderate basal ganglia/thalamic injury had cerebral palsy and 35% had developmental quotient less than 70 (40). Cerebral palsy was identified in 98% of infants with severe basal ganglia/thalamic injury 

Before Hbot:

I will post his MRI ( after Hbot a bit father in this article ok?)

3. So here we come fore 3d factor : did child was cooled after brain injury???? I believe that it’s helped to my child ( yes his body temperature was cooled it’s protocol for cardiac arrest but not always for HIE ).

4. Did child had 100% oxygen or just 30% oxygen delivery as Normobaric ? It’s may be has also role to play i think.

( it’s after reading this book I think about )

This lecture is also really good explanation why Hbot is better ( than Normobaric oxygen) we get oxygen in plasma! Lisen at 44minutes :

( and by the way I agree about multiple approach with Sherr – before starting Hbot in Israel’s for my son – we did batteries of blood tests and also tubes in ears – in order to protect them against barotraumatisme).

5. And you see naw what I think about Hbot ( we don’t have real agreement between doctors what is the best protocol for brain injury – and what kind brain injury ? By the way ?) TBI or anoxic? ). Parents has some possibilities: 1,5ata 100% oxygen is most used in hard chambers by centers ( sometimes is more pressure but honestly it’s the mostly use regiment for nerology in hard chambers) and I believe that in case of my son really oxygen in Hbot made biggest changes but as I posted before in Hbot conditions contrary to Normobaric 100% oxygen…

« We found that HBO, but not NBO, reduced oxygen and glucose deprivation-induced cell injury, indicating that passive tissue oxygenation (i.e. without vascular support) of the brain parenchyma requires oxygen partial pressure higher than 1 ATA. »

More about read my post in blog:

About other possibilitiy: 1,3ata without oxygen

Of cause first of all it’s the most “ not risky “ protocol for very injured children’s so may be also that’s why a lot doctors prefer start really very-law presssure ( case child brain really very damaged) and if child very small -very fragile.

So do the 1,3ata without oxygen will give same results for anoxic injury as 1,5ata 100% oxygen??? I don’t know 🤷‍♀️

I believe that in acute period use oxygen after anoxic injury just after it is more beneficial than without oxygen….. but it’s consern acute period 2-6-8 months after injury!!!!)

( I am not talking about CP-ok it’s chronic condition already) this we was discussed in study which compared pressures for cp.

So hope my reflections helps….

So for Marc Sudden cardiac arrest happens to my baby at 4 years old. Because of not diagnosed WPW.

He has cardiac arrest for 25 minutes

I did cpr with fiend ambulance was only after 20 minutes and his heart restarted only after 25 minutes…

He was on the hyperthermic protocol ( cooled)

His child body went through so much:

5 days comas

Blindness for 3 days after coma

He couldn’t talk at all for 2 weeks after ( and restarted very slowly to talk some words)

Wasn’t sitting for 1 month and we was 1 month in Intensive care unit and 4 months in hospital

He had 5 ablations ( for his heart syndrome in 3 years)

He was obliged to learn to do everything again… ( he was just 4 years boy when he has to pass through all this: When My son woke from life support after rewarming his body He had regular heard surveys 24h/24 because of regular SVT , kidney failure, respiratory failure & and he was on a feeding tube as well…. and he was blind and can’t talk….. but constantly crying…..only thing which calm his down a bit was my voice …

He has no memory of what happened but he has PTSD

He couldn’t feed himself

couldn’t stand

couldn’t walk

couldn’t do anything

We passed by phases : wheelchair and walker and he hate both of them….

But yes I am blessed that he is alive.

MRI’s after 80 hours Hbot in Israel:


M’y son Marc avant hbot juin 2016( main gauche)

Après 50 hbot: (septembre 2016)


right – before hbot 1 July 2016

Left – after 15 hours hbot -5 August 2016

PoNS: (started 29 March 2018)

Stairs before Pons (right vidéo septembre 2017)

After 6 months pons (left -September 2018)

Pons 6 mois ( left -June 2018/ right – September 2018)


Stoped using pons from 30 December 2018

So 2 AQM without pons:

AQM 1:(11 January 2019)

Aqm2( 28 January 2019)

Restarted using pons in Russia clinic : 11 February (2 weeks intensive in Moscow clinic with pons):

Aqm 3 (25 February )

I will do 4th AQM in September -October 2019 so hopefully I will get scientific datas for PoNS long therm use ….

If you want more read:

Normobaric or Hyperbaric?

1)Hyperbaric oxygen and hyperbaric air treatment result in comparable neuronal death reduction and improved behavioral outcome after transient forebrain ischemia in the gerbil:

« hyperbaric oxygen may represent a potentially important therapeutic option for post-arrest encephalopathy as well as other forms of brain injury. We also agree that animal studies of global brain ischemia suggest that hyperbaric oxygen may be beneficial with regard to neurologic outcome »

Anoxic brain injury resulting from cardiac arrest is responsible for approximately two-thirds of deaths. Recent evidence suggests that increased oxygen delivered to the brain after cardiac arrest may be an important factor in preventing neuronal damage, resulting in an interest in hyperbaric oxygen (HBO) therapy. Interestingly, increased oxygen supply may be also reached by application of normobaric oxygen (NBO) or hyperbaric air (HBA). However, previous research also showed that the beneficial effect of hyperbaric treatment may not directly result from increased oxygen supply, leading to the conclusion that the mechanism of hyperbaric prevention of brain damage is not well understood. The aim of our study was to compare the effects of HBO, HBA and NBO treatment on gerbil brain condition after transient forebrain ischemia, serving as a model of cardiac arrest.

Source :

2. this one also :Effects of normobaric versus hyperbaric oxygen on cell injury induced by oxygen and glucose deprivation in acute brain slices

« We found that HBO, but not NBO, reduced oxygen and glucose deprivation-induced cell injury, indicating that passive tissue oxygenation (i.e. without vascular support) of the brain parenchyma requires oxygen partial pressure higher than 1 ATA. »

Hypoxia and hyperbaric oxygen therapy: a review

Very good article to read: Hypoxia and hyperbaric oxygen therapy: a review

« The manner in which HBOT affects the body as a conse- quence of primary and secondary effects should be under- stood. The primary, or direct effects, include correcting the hypoxic condition by increasing oxygen delivery and tension, antimicrobial activity, and the attenuation of the HIF-mediated effects. The secondary effects include indirect consequences of HBOT, such as reducing the formation of ROS, increasing the body’s ability to heal, vasoconstriction, and angiogenesis, as well as subduing inflammation.57 The therapeutic pressures used in HBOT are described in terms of atmospheres of pressure ranging from 1.5 to 3.0 atm. In general, lower partial pressures are favored to avoid baro- trauma to the lungs, ear drums, sinuses, and teeth. Oxygen toxicity seizures are rare in clinical use of HBOT, but have been reported.58 Pressures and duration of HBOT differ between treatment centers, and standardized protocols require further investigation. »

« The secondary benefits of HBOT include reducing inflam- mation, attenuating reperfusion injury, promoting wound healing, and improving circulation. The primary benefits include increased oxygen tension, antimicrobial activity, and blocking HIF activity. Overall, HBOT is a safe and well- tolerated therapy when used under the direction of experi- enced and licensed treatment facilities. Side effects of HBOT are self-limiting and rare due to screening. HBOT has so many potential benefits and modalities for its use. It seems strange that HBOT has failed to gain widespread support. This is likely due to the history of HBOT and public opinion. »


HBOT has many current indications for treatment due to its ability to counter oxygen deficits, promote healing and angiogenesis, fight infection, and control inflammation. Inflammation is the body’s response to all insults and, in some instances, the body loses control over the system. This can lead to chronic disease or play a role in the development of disease. Evidence supporting the utility of HBOT as an anti-inflammatory treatment is growing. HBOT offers the possibility of a new drug class and will require more research to determine its dosing and indications for treating disease. The use of HBOT to treat the secondary injury process that causes damage in acute conditions could prove to be very valuable.56 Technological advances that make HBOT more available promote its potential to fight death and disability. »

Français ( en bref)

La manière dont l’OHB ( Hyperbare)affecte le corps à la suite d’effets primaires et secondaires doit être comprise. Les effets primaires, ou directs, incluent la correction de l’hypoxie en augmentant l’apport en oxygène et la tension, l’activité antimicrobienne et l’atténuation des effets induits par HIF. Les effets secondaires comprennent les conséquences indirectes de l’OHB, telles que la réduction de la formation de ROS, l’augmentation de la capacité de guérison du corps, la vasoconstriction et l’angiogenèse, ainsi que la maîtrise de l’inflammation.

Les pressions thérapeutiques utilisées dans l’OHB sont décrites en termes d’atmosphère de pression. (de 1,5 à 3,0 atm. )

En général, les pressions partielles plus basses sont privilégiées pour éviter les barotraumatismes des poumons, des tympans, des sinus et des dents.

Les crises convulsives dues à la toxicité de l’oxygène sont rares dans l’utilisation clinique de l’OHB mais ont été rapportées.

Les pressions et la durée de OHB diffèrent d’un centre de traitement à l’autre et les protocoles standardisés nécessitent des investigations complémentaires.

Les avantages secondaires de l’OHB comprennent la réduction de l’inflammation, l’atténuation des lésions de reperfusion, la promotion de la cicatrisation des plaies et l’amélioration de la circulation.

Les principaux avantages comprennent l’augmentation de la tension en oxygène, l’activité antimicrobienne et le blocage de l’activité HIF.

Dans l’ensemble, l’OHB est un traitement sûr et bien toléré lorsqu’il est utilisé sous la direction d’établissements de traitement expérimentés et agréés.

Les effets secondaires de l’OHB sont spontanément résolutifs et rares en raison du dépistage. L’OHB présente de nombreux avantages et modalités d’utilisation.

Il semble étrange que l’OHB n’ait pas réussi à obtenir un large soutien.

Cela est probablement dû à l’histoire de l’OHB ( Hyperbare) et à l’opinion publique.

l’OHB ( Hyperbare) a de nombreuses indications actuelles de traitement en raison de sa capacité à lutter contre les déficits en oxygène, à favoriser la guérison et l’angiogenèse, à lutter contre les infections et à contrôler l’inflammation.

L’inflammation est la réponse du corps à toutes les insultes et, dans certains cas, le corps perd le contrôle du système. Cela peut conduire à une maladie chronique ou jouer un rôle dans le développement de la maladie. Les preuves à l’appui de l’utilité de l’OHB en tant que traitement anti-inflammatoire se développent.

l’OHB ( Hyperbare) offre la possibilité d’une nouvelle classe de médicaments et nécessitera plus de recherche pour déterminer sa posologie et ses indications pour le traitement de la maladie.

L’utilisation de l’OHB ( Hyperbare) pour traiter le processus de blessure secondaire causant des dommages dans des conditions aiguës pourrait s’avérer très utile.

Les avancées technologiques qui rendent l’OHB ( Hyperbare) plus disponible renforcent son potentiel de lutte contre la mort et l’invalidité.


Not all text of this one,

But only conclusion : ( if someone wants to translate for us from Hebrew all text please contact me 🙂

could you please pm me? It looks interesting..

Heres the summary from google translate:

Hyperbolic Oxygen – Basic principles and new applications


Hyperbaric oxygen therapy is used as a primary treatment and as a complementary treatment for a wide variety of problems. Which can be classified into two groups of medical parenting: primary pressure treatment (eg The increase in the amount of free oxygen molecules during treatment in a pressure chamber allows for a diffuse force(Diffusion) is greater to the tissue and a significant increase in the amount of oxygen that reaches to the mitochondria in the cell.

The most common indications are related to the use of hyperbolic oxygen to treat wounds that are difficult to heal. With However, in a series of clinical and pre-clinical studies from recent years, it has been shown that the increase amount of oxygen in brain tissue damaged by injury so oxygen delivery with hyperbaric oxygen therapy has a beneficial effect In many physiological aspects: raising neroplasticity, restoring mitochondrial function, and creating blood vessels with improved local and systemic brain and blood vessels, changing the necessary environmental conditions The reduction of neuronal responses, and increased brain metabolism

The beneficial effect is in areas where there is a discrepancy between the anatomical damage And the metabolic functions of brain cells. Studies from recent years show that treatment Hyperbolic oxygen can play a significant role in brain rehabilitation processes in patients after Brain events, patients with neurogenic disorders after head trauma and in some patients With chronic pain syndrome (fibromyalgia). The new studies bring new insights into the Processes of healing and functioning of the brain and develop additional avenues of research.

Claudine Lanoix story and Hbot:

I just connected with Claudine Lanoix I really want to tell her Cp children’s story ( she promised to make her testimonials later so I will post it as well soon)

But she gave me permission to share all I wish about her sons story because as she said I me « I can’t tell you how happy I am that we have connected!! I give you my permission to share what ever I send you….It is my mission in this lifetime to have all children with anoxic or ischemic injury treated in HBOT as soon as possible after the event.  »

And just this article will tell you some part of her children’s story: « On January 5, 2019 Claudine Lanoix was recognized by the International Hyperbaric Association for her role in establishing hyperbaric oxygen as a treatment option providing significant benefits to children with neurological injuries. Claudine accepted the Vanguard award from Dr. Paul Harch at the January meeting of the International Hyperbaric Association. In receiving this award Claudine recognized her journey and the journey of all parents of children with neurological injuries and special needs.

Claudine, a mother of five, whose youngest sons (twins) were born prematurely at 27 weeks, developed Cerebral Palsy. Their journey took them to England, where they received hyperbaric oxygen therapy. Their lives were forever changed. Matthieu stepped from his wheelchair, walking without assistance for the first time. His brother Michel following treatments attained trunk control and was sit up without assistance, opened his hands so that he could feed himself and he began to speak for the first time at the age of 4 years.

Organizing and working with parents groups in Quebec and with the help of Dr Pierre Marois, a McGill Pilot study of 25 children with Spastic Diplegic Cerebral Palsy was conducted. Significant benefits were noted with improvement in Gross Motor Function, Fine Motor Function, reduction in spasticity. Improvements were also noted in speech, sleep and over all cognitive function.

These same findings were duplicated once again in a Multi-centre trial with 111 children in 2001 and validated in a 10 year follow-up published in 2014. The life changes are durable.

Twenty years later, Mathieu attends college with an area of study in Computer Sciences. Working at Best Buy as part of the Geek Squad over the Christmas Holidays, he set up new computers and repaired those that malfunctioned. Michel attends school working as a teacher assistant teaching immigrants English. Both speak French and English. Their changes were permanent. Their lives changed forever by HBOT. »

Hire find her story on YouTube

In order to wait you till she can testimonials by herself 😉

Naw she has hyperbaric center in Canada:

Centre Hyperbare De L’Ile // Island Hyperbaric Centre

website: email:

located at 117 Boul Cardinal Leger, in Pincourt, Quebec, Canada J7W 7A8 phone: 514-453-7978 // 1-866-677-7978

contact :Claudine Lanoix or Tiffany Nadeau – Thomas Fox

It is her mission : in this lifetime to have all children with anoxic or ischemic injury treated in HBOT as soon as possible after the event. 🙂

This one video her testimonials back in 2009:

And this one ( helping naw others children’s)




The article presents a comparative analysis of treatment of 76 pregnant women with diabetes mellitus type I, divided into two groups: basic and control. In the control group carried out conventional medical therapy, and patients of the main group along with those received courses of hyperbaric oxygenation. Evaluating the effectiveness of therapy based on the data of carbohydrate metabolism, glycated hemoglobin, Doppler and cardiotocography before treatment and after its completion. Shown that the use of hyperbaric oxygenation in complex treatment of pregnant women with diabetes mellitus type I reduces the complications of pregnancy, improve perinatal outcomes.

Yes in Russia we have studies with Hbot 1,3-1,5 ata for pregnant women’s with diabetes type 1 :

I will translate only final conclusion ok?

Material and research methods:

We evaluated the results of therapy in 76 pregnant women suffering from diabetes I, with single pregnancy. The contingent of the subjects was divided into two groups: the main and the control group. The main group consisted of 32 (42.1%) patients who received a comprehensive treatment of diabetes using HBO. All pregnant women admitted to hospital were given the standard medical treatment for diabetes mellitus I, which included insulin therapy. The use of another drug therapy depended on the complications of the course of pregnancy.

At the same time, pregnant women of the main group included in the complex of therapy sessions of HBO, which consisted in exposing the body to excessive atmospheric pressure of 1.3-1.5 atm. in baro-camera conditions. A single-use OKA-MT system (Russia) was used, equipped with an air conditioner of 54–58 A and designed for conducting sessions under conditions of elevated oxygen pressure. Mode of operation – one excess atmosphere. HBO courses included 5–7 daily sessions lasting 40 minutes each. Pregnant women received 3 courses of HBO. The first course was carried out in 6-8 weeks., The second – in 16-18 weeks. and the third in 22–24 weeks. of pregnancy.

The choice of these terms of pregnancy was determined by the most important periods of formation of the uteroplacental region. Since the earliest period of therapeutic effect on the blood flow in the uteroplacental region in order to correct its disorders can be considered 7–8 weeks. and 16-18 weeks. gestation, until the end of the first and second waves of cytotrophoblast invasion. When prescribing HBO sessions for pregnant women, absolute and relative contraindications were taken into account.

The treatment of the studied patients of both groups resulted in a decrease in the glycemia level. At the same time, in cases of applying HBO this decrease was more pronounced. If, prior to the courses of HBO, the glycemia level in the main group was on average 7.3 ± 1.3 mmol / l, after receiving the full course of HBO – 5.3 ± 0.7 mmol / l. In the same patients who received insulin therapy without HBO, glycemia indices did not differ significantly during the entire pregnancy and averaged 7.0 ± 1.3 mmol / l.

The criteria for the compensation of diabetes is not only noreglycemia, but also the normalization of the level of glycated hemoglobin.

On the background of treatment with HBO, there was a significant decrease in this indicator: from 7.1 ± 1.2 to 5.6 ± 0.7%. After conducting HBO courses in the studied patients, a significant improvement in Doppler data was observed. Indicators of uterine and fetoplacental blood flow increased by 32%, while in patients receiving conventional therapy, only by 17%. With the use of HBO, cardiotocography parameters improved: the amplitude of oscillations increased, the number of accelerations increased, and decelerations disappeared. The condition of all newborns was assessed on the Apgar scale.

In newborns from mothers who received traditional therapy, the Apgar score was in the first minute of life 7.2 ± 1.4 points, in the fifth minute 7.8 ± 1.2 points; in newborns from mothers who received HBO courses, in the first minute of life 7.6 ± 0.6 points, in the fifth minute 8.4 ± 0.7 points. Thus, both in the first minute and in the fifth minute, the average Apgar score in the main group was significantly higher compared to the control group. The frequency of neonatal asphyxia in the main group (1.3%) was significantly lower than in the control group (5.3%). The number of children born with signs of diabetic fetopathy in the main group (3.1%) was significantly lower than in the control group (9.1%).

T V Kuzenkova

Peoples, Friendship University of Russia

Department of Obstetrics and Gynecology with the course of Perenathology

I A Litvinenko

Peoples, Friendship University of Russia


Department of Obstetrics and Gynecology with the course of Perenathology

A A Lukaev

Peoples, Friendship University of Russia


Department of Obstetrics and Gynecology with the course of Perenathology

T V Zlatovratskaya

Clinical Hospital № 29

G S Bogdanova

Clinical Hospital № 29

T A Starceva

Clinical Hospital № 29

N T Tabatadze

Clinical Hospital № 29



Cerebral ischemia (CI) is damage to the brain tissue that occurs as a result of prolonged insufficient oxygen supply. CI occupies one of the most important places in terms of incidence and significance in the morbidity structure, making up 60-80% of all diseases of early childhood and occupying the 1st place in the structure of children’s disability. She is assigned the main role in the formation of the breakdown of the adaptive capacity of the newborn. Pathologically, this pathology is manifested in persistent hypoxia of brain tissue due to spasm of small blood vessels, a decrease in blood flow to the brain, and metabolic disorders in nerve cells [6, 12].

One of the pathogenetically substantiated non-drug methods of treating patients with this pathology is general magnetic therapy and hyperbaric oxygenation (HBO). Under our supervision there were 150 children of the first month of life with cerebral ischemia of moderate severity, hypertensive-hydrocephalic syndrome, who were hospitalized at MMU DGKB № 1 them. N.N. Ivanova G. O. Samara in 2009-2010 : (I can’t translate all study sorry)

So: Just part for 3 d group: Hbot+ magnetic therapy

Children III, the main group received a standard for this pathology drug therapy, a course of general magnetic therapy, and after it ended, they conducted a course of hyperbaric oxygenation (HBO). HBO was performed in the physiotherapy department of the MUH DGKB № 1 them. N.N. Ivanova in accordance with the requirements of ONTP 24-86 MVD, SNiP 11-69-78, GOST 12.2.052-81, OMU 42-21-26-88, GOST R 51316-99. Used pressure chamber BLKS – 3-01. The equipment is certified by the relevant authorities and approved by the Ministry of Health and Social Development of the Russian Federation and the Gosgortechnadzor of Russia to conduct HBO sessions.

Before the first session of HBO therapy, the parents of the children were introduced to the essence of the upcoming treatment in the pressure chamber, the requirements for the child’s clothes. When placed in the pressure chamber, patients were dressed in cotton underwear, and a cotton cap was put on their heads. For vacation sessions of hyperbaric oxygenation to children in the first months of life, we have developed a device in the form of a special L-shaped mattress. It is made of technical foam rubber, impregnated with flame retardant. The mattress is located in the pressure chamber, closing the input panel, but thus not preventing the child from moving [8].

Hyperbaric oxygenation was performed for children in an atmosphere of pure oxygen, carrying out a preliminary leaching regime, the pressure was raised to 0.2-0.4 ati, ( it’s means 1,2-1,4 ata total pressure) at a rate of 0.1 ati (1,1 ata) for 2 minutes, saturation for 15-20 minutes, decompression at 0.1 (1,1ata) at 1 minute . The duration of compression and decompression was 4 minutes each. The total duration of the session is 30 minutes. The course of treatment was 8-10 procedures carried out daily [3].

In children who received complex treatment in combination with HBO and general magnetic therapy, the most positive dynamics of NSDG parameters were observed. In 65.4% of patients in this group, a decrease in lateral ventricular indices was noted, in 72.1% a decrease in bone-brain diastasis, in 74.3% a decrease in the size of the interhemispheric fissure (p <0.05) compared with group 1 . In 23% of the observed children, the presence of periventricular leukomalacia was noted. She underwent a reverse development during treatment in patients in all three groups. However, we observed a significant decrease in the number of patients with such an ultrasound picture of the brain tissue only in children who received physiotherapy treatment.

Patients of group II compared in 22.5%, III, main group, in 47% (p <0.05). One third of children with cerebral ischemia under our supervision observed the presence of a pseudocyst or a symptom of « Swiss cheese. » Against the background of the therapy, statistically significant changes in the form of complete resorption of these formations or reduction of their size were noted only in the II and III groups – in 32.2% and 33.1%, respectively.

After treatment, all patients showed a positive trend in EEG indices. However, significant changes were noted only in children of groups II and III. So, the restoration of the picture of the zonal pattern of the electroencephalogram according to the age norm was observed in 29.4% of patients of group II and 36.5% of group III (p <0.05). Significant negative samples for hypercapnia and photostimulation were observed only in children of group III compared with data in children of groups I and II (p <0.05).

Thus, the proposed methods of non-pharmacological treatment of cerebral ischemia in children in the neonatal period can significantly improve the effectiveness of standard therapy for this pathology.

Пименов Ю.С., д.м.н., профессор, зав. кафедрой внутренних болезней НОУ ВПО «Самарский медицинский институт «РЕАВИЗ», г. Самара;

Богданова Л.П., д.м.н., профессор кафедры реабилитации и сестринского дела НОУ ВПО «Самарский медицинский институт «РЕАВИЗ», г. Самара.

HBOT efficacy in brain repair

The recent evidence for HBOT efficacy in brain repair and the new understanding of brain energy management and response to damage opens new therapeutically fields that will be further investigated in the upcoming years.

Very interesting article ( from pediatric doctor who had herself TBI and did Hyperbare in Israel)

Video :

Video is in English do listen it: (it’s explain really well about brain and why hbot can help neurological conditions : it’s started with strokes than TBI than fibromyalgia etc….)

« Clinical studies published in the last 3 years present convincing evidences that hyperbaric oxygen therapy (HBOT) can be the coveted neurotherapeutic method for brain repair. HBOT is a treatment in which oxygen-enriched air (up to 100%) is administrated to patients in a chamber where the pressure is elevated above 1ATA (one atmosphere absolute, which is the ambient atmospheric pressure). It is now realized, that the combined action of hyperoxia and hyperbaric pressure, leads to significant improvement in tissue oxygenation while targeting both oxygen and pressure sensitive genes, resulting in improved mitochondrial metabolism with anti-apoptotic and anti-inflammatory effects. In addition, the oxygen fluctuation generated by HBOT stimulates stem cells proliferation, HIF increased (The hyperoxide paradox) and brain angiogenesis. The lecture will introduce the current understanding of the multi-faceted role of HBOT in neurotherapeutics and the new understanding of brain energy management and response to trauma in general  »

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